The University of Utah's Center for Clinical 和 Translational Science (CCTS) 和 Program in Personalized Health has awarded grants to eight interdisciplinary projects to advance research 和 practices leading toward customizing healthcare to the individual patient.
"The grants were designed to combine talent, 资源, 和 perspectives from across disciplines in order to spur translational research related to 个性化的健康,” 迪尔先生.D., Executive Director of the Program in Personalized Health 和 Co-director of the Center for Clinical 和 Translational Science. "The research projects touch on a range of issues that need to be addressed as we move health care toward treating the right patient at the right time with the right intervention at the right cost."
This year's recipients come from 12 departments at the University of Utah School of Medicine, College of Pharmacy 和 College of Nursing, 和 include collaborations with ARUP Laboratories 和 Intermountain Healthcare, many of whom have benefited from CCTS' education 和 training 资源 for translational research including the KL2 Scholar Program (Tracy Frech, Robert Schlaberg), 和 Vice President's Clinical & Translational (VPCAT) 研究 Scholar Program (Mingan Chen, Lori Gawron, Robert Schlaberg).
"We are proud of their accomplishments 和 believe these training programs develop successful principal investigators,” Carrie Byington, M.D., Professor of Pediatrics, 和 Co-director of CCTS.
Grant recipients will carry out a variety of projects ranging from: developing novel immunotherapy treatments for multiple myeloma, to finding markers to identify Clostridium difficile infections that are refractory to treatment, to developing a decision support tool for counseling women with chronic diseases on contraception.
A total of $240,000 was awarded, with each project receiving $30,000. The seed grant awards are designed to position recipients for extramural funding.
研究 project titles 和 awardees are:
• Non-invasive, Host mRNA Biomarkers for Refractory Clostridium difficile Infection
梁振英，M.D., M.Sc. (Internal Medicine, infectious disease), Robert Schlaberg, M.D., MPh (Pathology, ARUP Laboratories) Bert Lopansri M.D. (Intermountain Healthcare)
• Development of a Combinatorial Cellular Immunotherapy for Multiple Myeloma
Djordje Atanackovic, M.D. (Internal Medicine/Hematology), Mingnan Chen, Ph.D. (Pharmaceutics 和 Pharmaceutical Chemistry)
• Tool to Optimize Use of BRCA Gene Testing in Families
Wendy Kohlmann (Population Health Sciences), Saundra Buys, M.D. (肿瘤)
• Study to Validate Statistical Prediction Models Derived from RNA Sequencing Data for Differential Diagnosis of Esophageal Eosinophilia
Mosaaki Yoshigi， M.D. (Pediatrics), Kathryn Peterson, M.D. (Internal Medicine/Gastroenterology)
• Assessing Quality of Care Across Three CTSA Institutions
戴安娜·布里克斯纳，R.Ph., Ph.D. (Pharmacotherapy), Bernie LaSalle (Biomedical Informatics)
• Prioritizing Personalized Reproductive Planning in the Silos of Subspecialty Care
Lori Gawron, m.m.D., MPH (OB/GYN), Katherine Sward, Ph.D.，注册护士（护理）
• Personalized Approach to the Scleroderma Esophagus
特蕾西·弗雷奇，m.s.D., M.S. (Internal Medicine/Rheumatology), Erinn Downs-Kelly, M.S.， DO（病理学）
• Impact of Psychological Profile 和 Socioeconomic Influences on Weight Recidivism Following Bariatric Surgery
安娜·贝利，M.D. (Surgery), Hillary Coon, Ph.D. (Psychiatry), Justin MacKenzie, Ph.D. (Physical Medicine 和 Rehabilitation)
The CCTS is committed to fostering multidisciplinary, 创新, clinical 和 translational research 和 fostering the development of novel translational research methods. Operating within the CCTS, the Program in Personalized Health is focused on engaging the entire University of Utah campus in the establishment of an integrated, patient centered realization of the promise of precision medicine. A personalized approach to patient care recognizes that each patient has a unique genetic makeup, is exposed to a unique set of environmental circumstances, 和 optimally benefits from interventions tailored to their individual needs.